Journal of diabetes science and technology
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J Diabetes Sci Technol · Mar 2012
Randomized Controlled Trial Multicenter Study Comparative StudyImpact of a modified needle tip geometry on penetration force as well as acceptability, preference, and perceived pain in subjects with diabetes.
Multiple factors impact subcutaneous insulin injection pain. Injection devices [e.g., syringe or pen needle (PN)] affect pain due to needle length, diameter, needle polishing and lubrication, and needle tip geometry. ⋯ Needle tip geometry affects penetration force. When blinded, patients did not distinguish differences in PN tip geometry with fine-gauge PN insertions. A 5-bevel needle tip is perceived as less painful and is preferred by subjects following home use for usual injections. Similar results occurred when patients were informed that they were using a needle with a modified tip.
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J Diabetes Sci Technol · Mar 2012
Multicenter StudyGlucose measurement of intensive care unit patient plasma samples using a fixed-wavelength mid-infrared spectroscopy system.
Glycemic control is a rapidly developing field in intensive care medicine with the aim of reducing mortality, morbidity, and cost. Current intensive care unit (ICU) glucose measurement technologies are susceptible to interference from medications, volume expanders, and other substances present in critically ill patients. We hypothesized that a fixed-wavelength mid-infrared (mid-IR) spectroscopy system would be accurate for measuring glucose levels of ICU patients. ⋯ These results suggest that a fixed-wavelength mid-IR spectrometer can measure glucose accurately in the plasma of ICU patients.