Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Dec 2020
Randomized Controlled TrialComparison of anesthesia effects between closed-loop and open-loop target controlled infusion of propofol using the bispectral index in abdominal surgery.
Bispectral index (BIS) can reflect the depth of propofol sedation. This study aims to compare the anesthetic satisfaction, anesthetic dose, and hemodynamic changes between closed-loop target controlled infusion (CLTCI) and open-loop target controlled infusion (OLTCI) during abdominal surgery. ⋯ Compared with propofol OLTCI, anesthesia with propofol CLTCI under BIS guidance can maintain a more appropriate depth of anesthesia sedation and more stable hemodynamics.
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2018
Randomized Controlled Trial[Continuous lumbar plexus block reduces the incidence of early postoperative cognitive dysfunction in elderly patients undergoing hip arthroplasty].
To observe the impacts of continuous lumbar plexus block (CLPB) on postoperative cognitive dysfunction (POCD) in elderly patients undergoing hip arthroplasty. Methods: Sixty elderly patients scheduled for hip arthroplasty with general anesthesia, were randomly allocated into a CLPB group and a PCIA group (n=30 each). In the CLPB group, lumbar plexus block was performed before trachea intubation, and CLPB was used for postoperative analgesia. In the PCIA group, intravenous analgesia was controlled in patients after operation. ⋯ Postoperative adverse events were recorded. Results: VAS scores at 12, 24, and 48 h after operation in the CLPB group were significantly lower than those in the PCIA group (P<0.05). Compared with the PCIA group, the MMSE scores were significantly higher (P<0.05), and the incidence of POCD at D1 and D3 was obviously reduced in the CLPB group (P<0.05). S-100β concentration at D1 and D3 in the CLPB group was significantly lower than that in the PCIA group (P<0.05). Conclusion: Application of CLPB in elderly patients undergoing hip arthroplasty could obviously relieve their postoperative pain, inhibit the production of S-100β, and reduce the incidence of early postoperative cognitive dysfunction.
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Apr 2018
Randomized Controlled Trial[Application of radial arterial puncture cannulation under ultrasonic guidance in patients with critical diseases].
To explore the clinicaleffect of radial arterial puncture cannulationunder ultrasonic guidance in patients with critical diseases. Methods: From December 2016 to May 2017, 120 patients under critical conditions in Department ofIntensive Care Unit, Xiangya Hospital, Central South University, who received arterial cannulation, were randomly divided into 2 groups: a control group (traditional blind puncture method) and an observation group (ultrasound-guided radial arterial cannulation) (60 cases in each group). The success ratio of radial arterial puncture cannulation by one time, total success ratio of radial arterial puncture cannulation, numbers of puncture, the rate of complications and the time of consumption were compared between the 2 groups. Results: There was no statistically significant difference in the total success ratio of radial arterial puncture cannulationin the 2 groups (P>0.05). The success ratio radial arterial puncture cannulation by one time was significantly greater in the observation group than that in the control group (P<0.05); the numbers of puncture, the rate of complications and the time of consumption in the observation group were lower than those in the control group, with statistically significant (all P<0.05). Conclusion: The application of ultrasound-guided radial arterial puncturecannulation can improve the success ratio of radial arterial puncturecannulation by one time, decrease the numbers of puncture, reduce the incidence of complications and save operation time.
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2016
Randomized Controlled Trial[Incidence of the post-operative cognitive dysfunction in elderly patients with general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia].
To explore the effect of general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia on the incidence of the post-operative cognitive dysfunction (POCD) in elderly patients. ⋯ The general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia can effectively maintain the stable hemodynamic status in the patients and display inhibitory effect on postoperative cognitive dysfunction.
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Sep 2015
Randomized Controlled Trial Comparative Study[Efficacy of different methods of anesthesia on children underwent hypospadias surgery].
To assess the efficacy of different methods of anesthesia on children underwent hypospadias surgery. ⋯ The laryngeal mask airway under general anesthesia combined epidural block is a better choice for children scheduled for hypospadias angioplasty.