Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2005
Randomized Controlled Trial[Effects of ulinastatin on cerebral inflammatory response during cardiopulmonary bypass].
To investigate the effects of ulinastatin (UTI) on cerebral inflammatory response during cardiopulmonary bypass (CPB). ⋯ Systemic and cerebral activation of inflammatory response during CPB can be alleviated by ulinastatin.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jun 2005
Randomized Controlled Trial Comparative Study[Isobaric and hyperbaric local anesthetic used in spinal anesthesia].
To reveal the advantages and disadvantages of the application of isobaric and hyperbaric local anesthetic in spinal anesthesia so as to provide reference for clinical practice. ⋯ Isobaric solution is superior to hyperbaric solution in spinal anesthesia.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jun 2005
Randomized Controlled Trial[Two-stage administration sedation method for gastroscopy in hypoxia predisposed patients].
To explore the safety and the efficacy of two-stage administration sedation method (with propofol plus midazolam) in the analgesia gastroscopy for hypoxia predisposed patients. ⋯ The two-stage administration sedation method is a new effective and safe sedation method for gastroscopy in the hypoxia predisposed patients.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Feb 2005
Randomized Controlled Trial[Effects of fentanyl on cytokines and MDA during cardiopulmonary bypass in patients undergoing valve replacement].
To investigate the effect of fentanyl on cytokines and MDA in valve replacement surgery during cardiopulmonary bypass ( CPB). ⋯ CPB leads to a proinflammatory and antiinflammatory response, as well as oxygen free radicals release. Larger dose fentanyl seemed to be effective in reducing CPB-induced inflammatory response and ischemic reperfusion injury, but the effect was not dependent on dose while fentanyl dose reaching some value, at the same time the duration of stay in ICU and time of endotracheal extubation is longer.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Feb 2005
Randomized Controlled Trial[Clinical research of hyperbaric, isobaric, and hypobaric solutions of bupivacaine in continuous spinal anesthesia].
To compare the anesthesia properities of hyperbaric bupivacaine with those of isobaric and hypobaric solutions when administered in the supine position undergoing hip surgery or lower limb surgery using continuous spinal anesthesia. ⋯ The 0.375% Isobaric bupivacaine used during contiuous spinal anesthesia in the supine position produces a suitable and a more "controllable" anesthesia, but a minimum dosage of 10 approximately 12.5 mg is required to obtain adequate anesthesic conditions with moderate hemodynamic changes and satisfying analgesia effects. Under similar conditions, 0. 375% hyperbaric bupivacaine produces major hemodynamic consequences with high cephalad spread and 0. 375% hypobaric bupivacaine has a too long onset time.