Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Evaluation of monitoring cardiac output by long time interval analysis of a radial arterial blood pressure waveform using the MIMIC II database.
We recently proposed a technique to estimate relative cardiac output (CO) change by unique long time interval analysis (LTIA) of a radial arterial blood pressure waveform. Here, we evaluated the technique in 169 critically ill patients, while comparing it to previous "pulse contour analysis" techniques, using the public MIMIC II database. ⋯ However, the average absolute thermodilution CO change in each patient was only 12.3%. As the absolute CO change increased, the LTIA technique became increasingly more accurate than the previous techniques.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
A closed-loop brain computer interface for real-time seizure detection and control.
The worldwide prevalence of epilepsy is approximately 1%, and 25% of epilepsy patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative and effective alternative. ⋯ A wireless communication feature also provided flexibility for subjects freeing from the hassle of wires. Experimental data from freely moving rats supported the functional possibility of a real-time closed-loop seizure controller.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Statewide validation of a patient admissions prediction tool.
We validate a proprietary system to predict hospital emergency department presentations. A key advantage in planning health service delivery requirements and catering for the large numbers of people presenting to hospitals is the ability to predict their numbers. Year-ahead forecasts of daily hospital presentations were generated for 27 public hospitals in Queensland, Australia from five years of historic data. ⋯ Emergency Department presentations were found to be not random and can be predicted with an accuracy of around 90%. Highest accuracy was over weekends and summer months, and Public Holidays had the greatest variance in forecast accuracy. Forecasts for urban facilities were generally more accurate than regional (accuracy is related to sample size).
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Support vector machine classification of multi-channel EEG traces: a new tool to analyze the brain response to morphine treatment.
The analgesic effect of morphine is highly individual, calling for objective methods to predict the subjective pain relief. Such methods might be based on alteration of brain response caused by morphine during painful stimuli. The study included 11 healthy volunteers subjectively quantifying perception of painful electrical stimulations in the esophagus. ⋯ The most discriminative feature was a decrease in the delta band (0.5 - 4 Hz) after morphine for volunteers with analgesic effect. Volunteers with no effect of morphine showed an increase in the delta band after drug administration. As only a proportion of patients benefit from opioid treatment, the new approach may help to identify non-responders and guide individualized tailored analgesic therapy.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Mechanical analysis of an oscillatory positive expiratory pressure device used in respiratory rehabilitation.
This article aims to characterize the mechanical behavior of the Acapella Blue, a respiratory rehabilitation device designed to aid sputum clearance. In this scope, the present study initially describes in detail the peak-to-peak oscillation amplitude (App) and peak frequency (fp) behavior, as well as positive pressure level (Ppl), in the flow range more comonly found in practice. The parameters were evaluated in all 5 adjustment levels of the equipment in intervals of 50 mL/s. ⋯ The studied device may produce oscillation in the ranges of ciliary movements and respiratory system resonance frequency of patients with respiratory diseases. Data obtained in this work may help to optimize the use of the Acapella Blue device in respiratory rehabilitation. Suggestions for the practical use of the device are also presented.