Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Steering deep brain stimulation fields using a high resolution electrode array.
Deep brain stimulation (DBS) therapy relies on electrical stimulation of neuronal elements in small brain targets. However, the lack of fine spatial control over field distributions in current systems implies that stimulation easily spreads into adjacent structures that may induce adverse side-effects. ⋯ Our computational analysis demonstrates that the DBS-array is capable of accurately displacing activation volumes with sub-millimeter precision. Our findings demonstrate that future systems for DBS therapy may provide for more accurate target coverage than currently available systems achieve.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Merging PK/PD information in a minimally parameterized model of the neuromuscular blockade.
A recursive system identification algorithm that merges PK/PD information in a minimally parameterized Wiener model for the NMB level is presented. The results show that the coupling between one parameter from the linear block and one from the static nonlinearity is advantageous, when evaluated on a database of 60 real collected NMB cases.
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Mining medical reports can reveal important information correlating diagnosis with raw measurements helping in decision support. In this paper we address the problem of finding similar measurement reports for aiding clinical decision support. ⋯ A document retrieval algorithm based on document class models is presented to enable similarity retrieval of pre-diagnosed reports. Collaborative filtering-guided assembly of associated disease labels is used to achieve clinical decision support.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Towards improved sedation control in critically ill patients.
Patients in intensive care units are often prescribed a combination of sedative and analgesic to manage anxiety and pain relief. Proper sedation management is crucial to patient recovery but few intensive care units routinely employ strategies that tailor drug delivery to ongoing patient needs. The Infuse-Rite has been developed to automate a protocol that eliminates the possibility of excessive sedation. Changing clinical demands have provided the impetus for ongoing enhancements to improve the sedation control of patients in intensive care.
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In recent years there has been a rapid growth in patient monitoring and medical data analysis using a number of computer-aided systems based on expert systems, fuzzy logic and many other intelligent techniques. Fuzzy logic-based expert systems have shown potential to improve clinician performance by imitating human thought processes in complex circumstances and accurately executing repetitive tasks to which humans are ill-suited. ⋯ The performance of the system was validated through a series of off-line tests. When detecting hypovolaemia a substantial level of agreement was observed between FLMS and the human expert (the anaesthetist) during surgical procedures.