Revista médica de Chile
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Revista médica de Chile · Nov 2019
Observational Study[Vitamin D levels among anesthesiologists and other physicians].
Background Sun exposure is the main source of 25-hydroxy-vitamin D. Since anesthesiologists work inside operating rooms, they are identified as a deficiency risk group. As medical activity in general occurs indoors, added to the work excess and sedentary lifestyle, physicians in general have low sun exposure. ⋯ The only protective factor was the intake of a vitamin D supplement (p < 0.01). Conclusions Anesthesiologists and other specialists were both at risk for vitamin D deficiency. Obesity was a risk factor and the use of a vitamin D supplement was the only protective factor.
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Interstitial lung diseases are a broad, diverse, challenging group of diseases, most of them chronic whose prognosis is not good. In the last two decades there have been considerable advances in the knowledge of the epidemiology, pathological and genetic bases and treatment of several of these diseases. This article summarizes and presents updated information about their classification, new knowledge on genetics and treatments in idiopathic pulmonary fibrosis, advances in the diagnosis and management of hypersensitivity pneumonitis and a review of the broad spectrum of interstitial diseases associated with connective tissue diseases. Several clinical trials are currently underway whose results will be available in the coming years and will provide more information and tools to improve the treatment of these patients.
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Revista médica de Chile · Nov 2019
Review[Clinical presentation and treatment of primary lipodystrophies].
Lipodystrophies are a heterogeneous group of syndromes defined by a severe reduction of the adipose tissue. These can be congenital or acquired. Anatomically, they can be partial or generalized. ⋯ The major complications of lipodystrophies are metabolic, often resulting in severe insulin resistance, diabetes and dyslipidemia. No cure is available for lipodystrophies but the supplementation with recombinant leptin potently controls the metabolic abnormalities when there is a leptin deficiency. Herein, we review the clinical presentation, diagnostic process and therapeutic principles of the main primary lipodystrophy syndromes.
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Revista médica de Chile · Nov 2019
Prognostic impact of renal failure recovery in patients with newly diagnosed multiple mieloma.
Background Renal failure (RF) is a common complication in patients with newly diagnosed multiple myeloma (NDMM). Aim To evaluate the frequency of RF in NDMM patients, and the prognostic impact of its reversibility. Material and Methods A retrospective study evaluating demographic and clinical characteristics of 154 consecutive patients with NDMM was carried out. ⋯ Median survival was 53, 27 and 6 months, respectively (p < 0.01). In the multivariate analysis, RF and hypercalcemia were independent predictors of a worse outcome. Conclusions Achieving a complete RR in patients with NDMM, is associated with a better survival.
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Revista médica de Chile · Nov 2019
[Factors influencing self-reported health in Chilean older people].
Background Self-reported health is subjective and depends on external factors such as socioeconomic status, presence of chronic diseases and working status, among others. Aim To determine which factors influence self-reported health among older people in Chile. Material and Methods A secondary analysis of the National Socioeconomic Characterization survey done in 2015. ⋯ Results The model had a good calibration and correctly classified 72 and 68% of men and women, respectively. The main factors that influenced health status self-perception were: not having health problems; having undergone a mental health interview, to receive supplemental nutrition, education, to have a productive work; and to having a social network. Conclusions There are health, cultural, economic and environmental factors that influence self-perceived health status.