Revista médica de Chile
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Revista médica de Chile · Mar 2021
[Analysis of 4,164 type 1 diabetes antibody profiles in a Chilean health centre].
Previous studies have assessed the role of Type 1 diabetes (DM1) antibodies as predictors of the natural history of disease. ⋯ Forty percent of DM1 antibody tests were positive. Among positive tests, 1, 2, 3 or 4 DM1 antibodies were detected in 48%, 33%, 17% and 3% of cases, respectively. The likelihood of testing positive was inversely related with age for ICA, GAD, IA-2, ZnT8 and directlyproportionalforIAA (p= -0,012; -0,013; -0,014; -0,009; 0,005 respectively). An association between DKA at the onset of the disease and IA-2 positivity was observed (Odds ratio (OR) 5.38 95% confidence intervals (CI) 1.79 - 16.16, P < 0.01). No association was found between IAA positivity and history of insulin therapy (OR 2.25 95%CI 0.63 - 7.90, P = 0.2403). The results obtained from this study represent a novel local profile of DM1 antibody data, highlighting a relationship between antibody positivity and age.
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Revista médica de Chile · Mar 2021
[Prevalence and repercussions of the locomotor syndrome in patients with chronic obstructive pulmonary disease].
Patients with Chronic Obstructive Pulmonary Disease (COPD) suffer a progressive deterioration of functional status and a decrease in independence in activities of daily living. Locomotor Syndrome (SL) is the involvement of the musculoskeletal system due to the deterioration caused by age. ⋯ LS in patients with COPD impacts their functional status and quality of life.
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Parathyroid carcinoma is a rare malignant disease that presents as a sporadic or familial primary hyperparathyroidism (PHP). The latter is associated with some genetic syndromes. It occurs with equal frequency in both sexes, unlike PHP caused by parathyroid adenoma that is more common in women. ⋯ Adjuvant therapies with chemotherapy or radiation therapy do not modify overall or disease-free survival. Recurrences are common and re-operation of resectable recurrent disease is recommended. The palliative treatment of symptomatic hypercalcemia is crucial in persistent or recurrent disease after surgery since morbidity and mortality are more associated with hypercalcemia than with tumor burden.
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Revista médica de Chile · Mar 2021
[Communication and empathy skills among health care workers of an emergency department of a general hospital].
Communication gaps are common in emergency medicine. ⋯ The health care team is not trained in communication skills, crisis intervention and empathy. Empathy and good communication are essential for users and family members to perceive health care as satisfactory and safe and to comply with indications. The lack of protocols to inform family members about the death of a patient is the finding that most clearly accounts for the observed communication deficiencies.