Revista médica de Chile
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Revista médica de Chile · Oct 2022
Review[Biological effects due to exposure to different concentrations of oxygen from hypo to hyperoxemia].
The systemic effects of oxygen deficiency or excess are not thoroughly described. Knowledge is evolving towards the description of beneficial and detrimental effects of both extremes of partial pressure of oxygen (PaO2). The cellular and tissue mediators derived from the modulation of the oxidative tone and the production of reactive oxygen species (ROS) are widely characterized biochemically, but the pathophysiological characterization is lacking. ⋯ On the other hand, the modulation of the hypoxic response associated with exposure to high altitude environments (hypobaric), favors Chile and its highlands as a natural laboratory to determine certain cardiovascular, cerebral and metabolic responses in the resident population. Also, the consequences of the intermittent exposure to high altitudes in workers also deserves attention. This review discusses the physiopathological response to hypo and hyperoxemia, associated with environments with different oxygen concentrations, and brings back the concept of oxygen as a pharmacological mediator in extreme environments such as high altitudes and hyperbaric medicine in divers, decompression sickness, osteonecrosis associated with radiotherapy and sudden sensorineural hearing loss.
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Revista médica de Chile · Oct 2022
Randomized Controlled Trial[Suturing basic procedural skills training for medical students during COVID-19 pandemic].
The adoption of sanitary measures due to the SARS-CoV-2 pandemic hampered teaching and learning methods in medicine. ⋯ Despite all the limitations of the pandemic context, we achieved a significant improvement after the intervention and a very good perception by the students.
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Revista médica de Chile · Oct 2022
[Motivation and satisfaction of medical students participating in an educational intervention on Pathology].
Undergraduate Pathology training in medicine is based on modalities centered on the teacher and associated with controlled motivation, with low satisfaction with the educational process. According to the Self-determination Theory, an early participation with responsibilities in clinical practice and an educational environment that promotes autonomy and basic psychological needs satisfaction (BPNS), would generate intrinsic motivation. ⋯ DPC is an innovative, feasible and attractive methodology for Pathology learning, with a high degree of satisfaction and intrinsic motivation. This experience can be extended to similar disciplines.
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Revista médica de Chile · Oct 2022
Case Reports[Sulfhemoglobinemia secondary to the use of zopiclone. Report of two cases].
Sulfhemoglobin (SulfHb) is formed by hemoglobin (Hb) oxidation by sulfur compounds. Sulfhemoglobinemia is mainly associated with drugs or intestinal bacterial overgrowth. Patients present with central cyanosis, an abnormal pulse oximetry and normal arterial oxygen partial pressure. ⋯ This is attributed to a similar absorbance peak of both pigments in arterial blood. Venous co-oximetry can be useful in this context. SulfHb is a self-limited condition in most cases, however it must be differentiated from methemoglobinemia to avoid inappropriate treatments like methylene blue.
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Revista médica de Chile · Oct 2022
[Psychometric properties of two surveys about beliefs towards vaccines in general and SARS-CoV-2 vaccine].
Negative beliefs about vaccines can threaten herd immunity and pandemic control. Although beliefs about vaccines influence vaccination intention, there are no valid instruments that evaluate this in the Latin American population. ⋯ The scales evaluated here are reliable and valid measures that showed associations with vaccination intention in the Chilean population.