Revista médica de Chile
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Revista médica de Chile · Mar 2023
[Putative mechanisms of action of electronvulsive therapy in affective disorders, a review].
The mechanisms of action (MA) of electroconvulsive therapy (ECT) in affective disorders are poorly understood. We synthesized and discussed the evidence provided by primary studies and systematic reviews in humans. There are differences in the methylation of candidate genes involved in the response to ECT. ⋯ In PMDD, multiple inflammatory mediators were associated with the clinical response (natural killer cells, tumor necrosis and growth factors, and interleukins 1, 4, 6, 10,1β). Likewise, some structures and circuits consistently involved at the morphological and functional level are the default mode network, cognitive control networks, frontal, temporal, cingulate, occipital and temporal cortices, frontal, temporal, precentral, fusiform and left angular gyri, hippocampus, thalamus and amygdala. Investigations are mostly focused on PMDD, are observational, and their samples limited, but they show relatively consistent results with clinical significance.
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Revista médica de Chile · Mar 2023
Food insecurity in Chilean university students during the COVID-19 pandemic.
Food and nutrition were affected by the COVID-19 pandemic, increasing levels of food insecurity. University students were a risk group for food insecurity due to the closure of educational establishments where they received their main meals. ⋯ Undergraduate students are vulnerable to food insecurity. Mitigation actions should be carried out when educational establishments are closed.
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Revista médica de Chile · Mar 2023
Observational Study[Use of medicinal plants among older people attending a public primary care center].
The use of medicinal plants is common among a significant part of the elderly population. In addition, at present, the use of medicinal plants has been introduced in Primary Health Care centers, and is becoming increasingly popular, especially in this population. ⋯ The results reinforce the importance of knowing the plant species used by the population and the correct orientation on their rational use, potential benefits, adverse effects and interactions.
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Revista médica de Chile · Mar 2023
Case Reports[Intracranial hypertension syndrome as an unusual manifestation of Sjögren's syndrome. Report of one case].
Neurological manifestations such as polyneuropathy are reported in 8-49% of cases with Sjögren's Syndrome (SjS), but central nervous system involvement is seldom described. We report a 46-year-old woman with a history of SjS with distal renal tubular acidosis and autoimmune thyroiditis. She consulted in the emergency room for a five-days history of holocranial headache and explosive vomiting. ⋯ Brain AngioCT ruled out thrombosis, and brain magnetic resonance (MRI) was without structural alterations or hydrocephalus. Lumbar puncture had increased cerebrospinal fluid output pressure but without cytochemical alterations, and negative gram, cultures and filmarray. The diagnosis of Intracranial Hypertension Syndrome (ICHTS) ofprobable autoimmune etiology in the context of SjS was proposed, and management with high-dose corticosteroids was initiated with favorable clinical and imaging response.
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Revista médica de Chile · Mar 2023
[Living-donor kidney graft ex vivo endoscopic nephrolithotomy with flexible instrument].
The finding of an asymptomatic stone in the study of a living kidney donor does not necessarily contraindicate donation, however, there is no consensus on the management of these cases. The use of a graft with lithiasis may represent a risk of recurrence in the remaining kidney in the donor and eventual obstructive complications in the transplanted kidney. The objective of this work is to present the usefulness of ureteroscopy (URS) to resolve lithiasis ex vivo before transplantation. ⋯ In this experience, the URS of the donor kidney was a feasible procedure and was not associated with adverse consequences for the graft. The main advantage of this procedure is to avoid the potential risk to the recipient of an obstructive graft complication.