Revista médica de Chile
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Revista médica de Chile · Apr 2024
[Assessment of diagnostic utility of cerebrospinal fluid flow cytometry immunophenotyping and cytology in B cell non- Hodgkin lymphoma in a public chilean hospital].
Cerebrospinal fluid (CSF) involvement in B cell non-Hodgkin lymphomas is a poor prognostic sign and diagnosis is made using techniques such as flow cytometry (FCM) and conventional cytology (CC). ⋯ A higher proportion of infiltration cases were detected by CMF than by CC. In valuable cases, CC complements CMF.
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Revista médica de Chile · Apr 2024
[Implications of cyberbullying in major depressive symptoms development in young people between 15 and 29 years of age in Chile].
The use of digital means of communication and socialization among young people brings with it new stressors, risks, and forms of ag- gression, such as cyberbullying. ⋯ The results reflect various factors of emerging adulthood that make this group more vulnerable, emphasizing the importance of studying the phenomenon at non-school ages since this form of aggression is not exclusive to adolescence, and neither are its effects on mental health.
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Revista médica de Chile · Apr 2024
Review Case Reports[Transformation of Follicular Lymphoma into Composite Lymphoma: A Case Report and Literature Review].
Follicular lymphoma is a relatively indolent B-cell lymphoma composed of neoplastic centrocytes and centroblasts. The histologic transformation of follicular lymphoma is a well-described phenomenon with an average risk of 30% at ten years. The occurrence of Hodgkin lymphoma after follicular lymphoma, as well as composite lymphoma, is extremely rare. ⋯ A lymph node biopsy three years later revealed persistent follicular lymphoma, after which the patient received radiotherapy. The patient returned with progressively enlarging axillary lymph nodes five years later. A lymph node biopsy demonstrated a composite lymphoma that was consistent with follicular lymphoma and Hodgkin lymphoma.
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Revista médica de Chile · Apr 2024
Review[Endocrinological Effects of Lithium: Pathophysiological Mechanisms and Clinical Implications].
Lithium carbonate has a narrow therapeutic range capable of producing various adverse effects; despite this fact, it is used as first-line therapy in patients with bipolar disorder (BD) thanks to its high effectiveness. Among its adverse events are several conditions at the endocrine level, such as hypothyroidism, hyperthyroidism, hypercalcemia, hyperparathyroidism, and nephrogenic diabetes insipidus. The adherence to current guidelines for monitoring those events is low. The objective of this review is to provide insight into the pathophysiological mechanisms of the endocrine effects of lithium and give recommendations based on the current literature for the monitoring and treatment of these conditions.
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Revista médica de Chile · Apr 2024
Review[Decision-Making by Hospital Teams Regarding Access and Use of Life-Support Technology and End-of-Life Processes in Critically Ill Adult Patients: A Narrative Review].
Death processes have been progressively transferred to hospital spaces due to biomedicalization and the use of technologies, generating important challenges for healthcare systems. The COVID-19 pandemic exposed the lack of unified criteria and principles for a dignified death in the hospital. This study corresponds to a narrative review using Higgins & Green's methodological framework as a reference. ⋯ The evidence shows variability in decision-making associated with the clinical status of the patient, the criteria of the medical professional, added to structural elements of the health system and political-legal aspects. The literature recommends reflexive, dynamic, flexible, and individualized decision-making processes that consider the patient's preferences, clinical judgment, prognosis, and available resources. Communication, advance care planning, interdisciplinary discussions, external consultations, and the involvement of ethical committees are crucial throughout the process.