Otolaryngologia polska. The Polish otolaryngology
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Comparative Study
[Otoacoustic emissions measurements in children during the chemotherapy because of the acute lymphoblastic leukemia].
Chemotherapy is associated with an increased risk of ototoxic changes. The predictive value of conventional pure-tone audiometry on early detection of ototoxicity has been questioned. Otoacoustic emissions (OAEs) appear to be more sensitive to cochlear insult than the conventional pure-audiometry. The purpose of our study was (a) investigation the clinical usefulness of Distortion Product Otoacoustic Emissions (DPOAEs) as early indicator of chemotherapy-induced ototoxicity, (b) determination which of the protocols of chemotherapy is most ototoxic as measured by DPOAEs, (c) comparison of the short-term and long-term effects of chemotherapy on DPOAEs. ⋯ Distortion product otoacoustic emissions measurements are very sensitive on early detection of the changes in cochlear function and are recommended for monitor hearing in patients during chemotherapy.
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Biography Historical Article
[Tadeusz Antowski Ph.D. (1919-1966), from ENT Unit in Dachau to the lectureship in Otolaryngological Clinic of Poznań University].
The authors present the biography of the laryngologist Tadeusz Antowski Ph. D. (1919-1966). The medical studies at the University of Poznań, which he started with his brother Marian (1915-1943), were interrupted by World War II. ⋯ Soon he was called up to the military service and in 1951 became the chief of Otolaryngological Department in the 8-th Army Hospital in Toruń. He was an active member of Polish Medical Association and the president of the Toruń branch. Tadeusz Antowski died on 02.11.1966 in Gdańsk.
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The aim of the study was to assess the influence of hyperbaric oxygen on regeneration processes which take place in the inner ear (basilar papilla - BP) of chicken after exposure to wide-band noise at the level 120 dB for 48 hours. We found, that hyperbaric oxygen applied once a day after exposure to the noise restricted he extensiveness and decreased the dynamics of hair cells injury. Quantative and qualitive differences in histological changes which take place in chick basilar papilla after exposure to hyperbaric oxygen and glucocorticoids may prove the presence of different their effectory points of acting.