Medicinski pregled
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Affection of the abdominal organs with sarcoidosis is a part of the generalized granulomatous diseases with clinical manifestations that vary depending on the affected organ. ⋯ Examinations of abdominal organ involvement should be a standard procedure in each patient affected with sarcoidosis.
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A 45-year-old female patient with diabetes was on corticosteroid therapy for a year due to pulmonary sarcoidosis. During the last six years she was treated with oral antidiabetic drugs, but during the last couple of months, she required insulin therapy due to impaired glycoregulation. After corticosteroid therapy was discontinued, glycoregulation improved and insulin therapy was discontinued as well. ⋯ Diabetic patients with sarcoidosis who need corticosteroid therapy, should control glycoregulation Patients with sorcoidosis, treated with corticosteroid therapy need regular control in order to diagnose early diabetes.
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Radiofrequency ablation is a new invasive procedure that is being increasingly used in the treatment of colorectal liver metastases. Resection as the only potential cure for colorectal liver metastases is limited by the size and the itrahepatic localization of lesions. Radiofrequency ablation may extend the limitations of classic surgery. In this work we analyzed the combination of surgical liver resection and radiofrequency ablation of liver metastases. ⋯ A combination of liver resection and radiofrequency ablation in treatment of advanced colorectal cancers with liver metastases is a good treatment modality which increases the number of operabile cases.
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Sarcoidosis is a granulomatous disease that may involve multiple organ systems. Cardiac sarcoidosis may be a primary or a secondary process. Clinical manifestations of cardiac sarcoidosis include impulse conduction disorders, various arrhythmias, symptoms and signs of heart failure and even sudden death. The aim of the present paper was to assess the possibilities for echocardiographic detection of pathological changes in the hearts of patients with diagnosed systemic sarcoidosis. ⋯ Echocardiography is a very useful method for obtaining important information on morphological and functional changes in myocardium of patients with sarcoidosis. However, neither of previously mentioned echocardiographic signs is specific for cardiac sarcoidosis. The diagnosis of cardiac sarcoidosis cannot be made solely on the basis of echocardiographic findings. Other diagnostic procedures, from clinical findings to endomyocardial biopsy, must be employed as well.
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Health-related quality of life in interstitial lung diseases, especially in sarcoidosis, has hardly received appropriate attention in clinical studies due to lack of validated methods of measurement. Until now, in patients with sarcoidosis and interstitial lung diseases, several generic and respiratory specific quality-of-life instruments were used in order to discover the most valid and reliable quality-of-life instrument. Sarcoidosis is a multi-system disease that affects quality of life in many different ways. ⋯ The first sarcoidosis specific questionnaire shows perfect correlation with the possible clinical course in patients with sarcoidosis.