Mayo Clinic proceedings
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Mayo Clinic proceedings · Jun 2013
Review Meta AnalysisL-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis.
To evaluate the effects of L-carnitine compared with placebo or control on morbidity and mortality in the setting of acute myocardial infarction. ⋯ Compared with placebo or control, L-carnitine is associated with a 27% reduction in all-cause mortality, a 65% reduction in VAs, and a 40% reduction in anginal symptoms in patients experiencing an acute myocardial infarction. Further study with large randomized controlled trials of this inexpensive and safe therapy in the modern era is warranted.