Mayo Clinic proceedings
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Mayo Clinic proceedings · Dec 2014
Review Meta Analysis Comparative StudyComparative efficacy of biologic therapy in biologic-naïve patients with Crohn disease: a systematic review and network meta-analysis.
To study the comparative efficacy of biologic therapy in the management of biologic-naïve patients with Crohn disease (CD). ⋯ On the basis of network meta-analysis, IFX may be most efficacious agent for inducing remission in CD in biologic-naïve patients. In the absence of head-to-head treatment comparison, the confidence in these estimates is low. Future comparative efficacy studies are warranted.