Mayo Clinic proceedings
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Mayo Clinic proceedings · May 2014
ReviewContemporary strategies in the diagnosis and management of heart failure.
Heart failure (HF) is an important public health problem, and strategies are needed to improve outcomes and decrease health care resource utilization and costs. Its prevalence has increased as the population ages, and HF continues to be associated with a high mortality rate and frequent need for hospitalization. The total cost of care for patients with HF was $30.7 billion in 2012, and it is estimated to more than double to $69.8 billion by 2030. ⋯ We are in the midst of a rapid evolution in our ability to care for patients with end-stage HF (stage D) because of the introduction of and improvements in mechanical circulatory support. Left ventricular assist devices used as destination therapy offer an important therapeutic option to patients who do not qualify for heart transplant because of advanced age or excessive comorbidity. This review provides a thorough update on contemporary strategies in the diagnosis and management of HF by stage (A to D) that have emerged during the past several years.
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Mayo Clinic proceedings · May 2014
Comparative StudyComparative effectiveness of telaprevir-based triple therapy in patients with chronic hepatitis C.
To examine the effectiveness and tolerability of triple therapy with pegylated interferon (p-IFN), ribavirin (RBV), and telaprevir in patients with chronic hepatitis C receiving treatment in an academic practice setting and in a more clinically diverse population compared with patients receiving treatment in phase 3 trials. ⋯ Telaprevir-based triple therapy in clinical practice is considerably more effective than dual therapy with p-IFN and RBV despite the significant degree of anemia that complicated therapy, requiring RBV dose reduction and erythropoietin support.
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Mayo Clinic proceedings · May 2014
Impact of prior admissions on 30-day readmissions in medicare heart failure inpatients.
To determine how all-cause hospitalizations within 12 months preceding an index heart failure (HF) hospitalization affect risk stratification for 30-day all-cause readmission. ⋯ In Medicare inpatients with HF, prior all-cause admissions strongly increase all-cause readmission risk and markedly improve risk stratification for 30-day readmission.
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Mayo Clinic proceedings · May 2014
Biography Historical ArticleSolomon's Seal, Flamingo Flower, Kousa Dogwood, and Kousa Dogwood by Harold Feinstein.
In recognition of the important part that art has had in the Mayo Clinic environment since the original Mayo Building was finished in 1914, Mayo Clinic Proceedings will feature some of the numerous works of art displayed throughout the buildings and grounds on the Mayo Clinic campuses.