Mayo Clinic proceedings
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Mayo Clinic proceedings · Oct 2019
Comparative StudySurvival Benefit of Obese Patients With Pulmonary Embolism.
To investigate the impact of obesity and underweight on adverse in-hospital outcomes in pulmonary embolism (PE). ⋯ Obesity is associated with decreased in-hospital mortality rates in patients with PE. Although obese patients were more often treated with reperfusion therapies, the survival benefit of obese patients occurred independently of age, sex, comorbidities, and reperfusion treatment.
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Mayo Clinic proceedings · Oct 2019
Cumulative Doses of Ionizing Radiation From Computed Tomography: A Population-Based Study.
To assess cumulative radiation doses from computed tomography (CT), patient characteristics, and clinical indications for CT in a population-based sample. ⋯ Exposure to ionizing radiation from CT occurred disproportionally in specific subgroups of the population. A limited number of clinical indications contributed the majority of radiation among adults with high doses.
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Mayo Clinic proceedings · Oct 2019
Editorial CommentObesity Paradox in Pulmonary Embolism: Myth or Reality?
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Pure autonomic failure (PAF) is a neurodegenerative disorder of the autonomic nervous system clinically characterized by orthostatic hypotension. The disorder has also been known as Bradbury-Eggleston syndrome, named for the authors of the 1925 seminal description. Patients typically present in midlife or later with orthostatic hypotension or syncope. ⋯ With widespread involvement, patients may present to a variety of different specialties and require multidisciplinary treatment approaches. Pathologically, PAF is characterized by predominantly peripheral deposition of α-synuclein. However, patients with PAF may progress into other synucleinopathies with central nervous system involvement.