Shanghai kou qiang yi xue = Shanghai journal of stomatology
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Shanghai Kou Qiang Yi Xue · Dec 2016
[Correlations of plasma concentrations of β-amyloid peptide and S-100β with postoperative cognitive dysfunction in patients undergoing oral and maxillofacial cancer surgery].
To evaluate the changes of perioperative plasma concentrations of Aβ1-40 and S-100β to determine the relationship with postoperative cognitive dysfunction in elderly patients undergoing oral and maxillofacial cancer surgeries. ⋯ POCD was present in 32.2% of patients on day 7 after oral and maxillofacial surgeries with general anesthesia. The increasing levels of Aβ1-40, S-100β may be associated with the occurence of POCD. Patients with long-lasting operation and high concentrations of Aβ1-40 and S-100β after surgeries were at a higher risk of POCD. The clinical values of Aβ1-40 and S-100 as predictive measurements of POCD after oral and maxillofacial cancer surgery appear to be reasonable.