The journal of allergy and clinical immunology. In practice
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J Allergy Clin Immunol Pract · May 2017
Multicenter StudySevere Cutaneous Adverse Drug Reactions in Pediatric Patients: A Multicenter Study.
The severe cutaneous adverse drug reactions (SCARs) are rare but could be life-threatening. These include drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis. ⋯ SCARs in children are not common but potentially serious. Early diagnosis and appropriate treatment of SCARs will reduce the incidence of morbidity and mortality.