The journal of allergy and clinical immunology. In practice
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J Allergy Clin Immunol Pract · Jan 2021
Meta AnalysisAntineutrophil Cytoplasmic Antibodies and Organ-Specific Manifestations in Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review and Meta-Analysis.
Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a rare and often severe systemic vasculitis associated with antineutrophil cytoplasmic antibodies (ANCAs). EGPA can affect multiple organ systems, but the relationships between ANCA status and the organ-specific manifestations of EGPA in previous reports were inconsistent. ⋯ This study provides more evidence that patients with EGPA may exhibit different features of disease based on their ANCA status.