The journal of allergy and clinical immunology. In practice
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J Allergy Clin Immunol Pract · May 2013
Case ReportsImmediate allergic hypersensitivity to quinolones associates with neuromuscular blocking agent sensitization.
We identified a case of quinolone allergic hypersensitivity associated with quaternary ammonium (QA) sensitization, the allergic determinant of neuromuscular blocking agents (NMBAs). Concomitant sensitization to several chemically different drugs is rarely reported and raises the question of a nonfortuitous association. ⋯ We report here the first documentation of a high prevalence of QA sensitization in patients with quinolone allergic hypersensitivity. These results suggest a new way for NMBA sensitization. It thus seems appropriate to investigate NMBA sensitization when quinolone allergic hypersensitivity is diagnosed.
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J Allergy Clin Immunol Pract · Jan 2013
Case ReportsVocal cord dysfunction related to water-damaged buildings.
Vocal cord dysfunction (VCD) is the intermittent paradoxical adduction of the vocal cords during respiration, resulting in variable upper airway obstruction. Exposure to damp indoor environments is associated with adverse respiratory health outcomes, including asthma, but its role in the development of VCD is not well described. ⋯ VCD can occur with exposure to water-damaged buildings and should be considered in exposed patients with asthma-like symptoms.