Allergie et immunologie
-
Cold urticaria is characterized by the development of urticaria, usually superficial and/or angioedematous reaction after cold contact. It was found predominantly in young women. The diagnosis is based on the history and ice cube test. ⋯ Doxepin may be useful in the treatment. Leukotriene receptor antagonists may be a novel, promising drug entity. In patients who do not respond to previous treatments, induction of cold tolerance may be tried.
-
Allergie et immunologie · Sep 2002
Review Comparative StudyAnaphylaxis to muscle relaxants: rational for skin tests.
IgE-dependent allergy to muscle relaxants (MR) has an estimated prevalence of 1 out of 6500 General Anesthesias (GA). 62% of anaphylaxis during surgery are due to MR anaphylaxis. All the molecules are divalent, carrying two NH4+ epitopes (quaternary ammonium ions), either structurally or after rapid in vivo protonization (vecuronium). The excellent overall performance of skin test makes them the golden standard for the diagnosis of anaphylactoid reactions. ⋯ Both types of tests can be used for the diagnosis. IDT have to be carried out for the search of the cross sensitization. 84% of patients do have cross sensitization to MRs but only 16% react to all MRs. The further use of MRs selected by negative IDTs has been proved to be safe.
-
Allergie et immunologie · Apr 2002
Review Case ReportsFood allergy and IgE sensitization caused by spices: CICBAA data (based on 589 cases of food allergy).
Spices originate in various botanical families: Apiaceae, Lamiaceae, Lauraceae, Leguminosae, Liliaceae, Myristicaceae, Myrtaceae, Piperaceae, Solanaceae, Zingiberaceae.... ⋯ Frequent sensitization to Apiaceae is observed: coriander, caraway, fennel, celery: 32% of prick-tests in children, 23% of prick-tests in adults. Sensitization to Liliaceae: garlic, onion, chive, is observed in 4.6% of prick-tests in children, 7.7% of prick-tests in adults. Rare cases of sensitization to paprika and saffron are recorded. Prick-tests to nutmeg, ginger and clove are currently negative. 10 food allergies related to the mugwort-celery-spices syndrome are reported: coriander: 1, caraway: 2, fennel: 3, garlic: 3, onion: 1. Food allergy to spices is unfrequent: 2% of the totality of food allergies. However, only adults are allergic to spices and allergy to spices accounts for 6.4% of food allergies in adults. Tiny amount of proteins are usually ingested. Patients at risk of spice allergy are young adults sensitized to mugwort and birch allergens, sharing cross-sensitization with various food vegetal allergens. The clinical suspicion raises from frequent post-prandial systemic reactions. Other allergens of vegetal origin have to be cleared. Diagnosis can be established by DBPCFC using powdered spices in capsules.
-
Drugs administrated to pregnant women must be carefully monitored. Prevention of dietary sensitization in foetus via the mother is still discussed. However, it must not induce any dietary deficiency to both the mother and the foetus. ⋯ Asthmatic pregnant women must be treated because under- or non treatment is more dangerous for both the woman and the foetus compared to eventual drug side effect. Asthma must be treated with inhaled glucocorticosteroid in order to be stabilized because giving birth is the only moment which can not be interrupted. Antihistamine-H1 which can be used during pregnancy are dexchlorpheniramine for the first and second third and cetirizine during the last third of the pregnancy.
-
Allergie et immunologie · Dec 2000
Review[Atopic dermatitis:epidemiologic, clinical features, the role of allergy (review)].
This review includes the main epidemiological, genetic, clinical, evolutionary, and treatment elements of atopic dermatitis with a special reference to allergy and non-allergy factors that trigger pulses of atopic dermatitis.