Yonsei medical journal
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Yonsei medical journal · Apr 2008
Randomized Controlled Trial Comparative StudyComparison of remifentanil and fentanyl for postoperative pain control after abdominal hysterectomy.
In this randomized, double-blind study, we investigated the analgesic efficacy and side effects of continuous constant-dose infusions of remifentanil after total abdominal hysterectomy and compared it to fentanyl. ⋯ Continuous infusion technique of remifentanil did not reveal any benefits compared to fentanyl. Furthermore, it is not safe for postoperative analgesia in the general ward.
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Yonsei medical journal · Apr 2008
Randomized Controlled TrialRemifentanil prevents withdrawal movements caused by intravenous injection of rocuronium.
The incidence of pain induced withdrawal movement following intravenous injection of rocuronium is high. This randomized, double-blind, placebo-controlled study was designed to evaluate the effect of pretreatment of remifentanil on the withdrawal movements due to intravenous injection of rocuronium during anesthetic induction. ⋯ The pretreatment with 0.5 and 1.0 microg/kg remifentanil of bolus doses prevented the withdrawal movements caused by rocuronium injection, and effectively blunted cardiovascular activation following tracheal intubation.