Yonsei medical journal
-
Yonsei medical journal · Jan 2014
Randomized Controlled TrialEffects of seasonal differences in testosterone and cortisol levels on pain responses under resting and anxiety conditions.
This study investigated whether hormones and pain perception are associated with exam anxiety, and also whether exam anxiety is affected by seasonal differences in testosterone and cortisol levels. ⋯ These results indicate that seasonal differences in testosterone and cortisol levels under anxiety and at rest may affect pain responses. These results also suggest that acute clinical pain may be relieved by managing anxiety that is related to a decrease of testosterone in spring and a large increase of cortisol in summer.
-
Yonsei medical journal · Jan 2014
Multicenter StudyClinical outcomes and prognostic factors of empirical antifungal therapy with itraconazole in the patients with hematological malignancies: a prospective multicenter observational study in Korea.
To identify prognostic factors for the outcomes of empirical antifungal therapy, we performed a multicenter, prospective, observational study in immunocompromised patients with hematological malignancies. ⋯ We concluded that empirical antifungal therapy with IV itraconazole in immunocompromised patients is effective and safe. Additionally, age over 50 years and poor performance status were poor prognostic factors for the outcomes of empirical antifungal therapy with IV itraconazole.
-
Yonsei medical journal · Jan 2014
Inhaled colistin for treatment of pneumonia due to colistin-only-susceptible Acinetobacter baumannii.
Colistin is used for the treatment of pneumonia associated with multidrug- resistant Acinetobacter baumannii and Pseudomonas aeruginosa. However, the best route of administration and dosage is not known. We report our experience with aerosolized colistin in twelve patients with pneumonia caused by colistin-only-susceptible (COS) A. baumannii. ⋯ Colistin inhalation therapy is deemed tolerable and safe, and could be beneficial as an adjuctive therapy for the management of pneumonia due to COS A. baumannii. However, the potential development of colistin resistance cannot be overlooked.
-
Yonsei medical journal · Jan 2014
Randomized Controlled TrialEpithelial wound healing after cataract surgery comparing two different topical fluoroquinolones.
To compare the epithelial wound healing response of two preservative-free fluoroquinolones, moxifloxacin and levofloxacin, in patients who underwent cataract surgery. ⋯ There were no differences on epithelial wound healing comparing these two different fluoroquinolones at the incision site of cataract surgery.