International journal of clinical practice. Supplement
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Int J Clin Pract Suppl · May 2015
ReviewHeadache: muscle tension, trigger points and referred pain.
Scientific interest in the pathogenesis of tension-type headache (TTH) has lagged behind that of migraine, although TTH is the most common headache disorder and considered the most important in terms of socioeconomic impact. As a result, understanding of the underlying mechanisms of TTH has remained relatively incomplete.
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Int J Clin Pract Suppl · May 2013
Qualitative echocardiography parameters for prediction of pulmonary hypertension.
Current guidelines recommend echocardiography as the preferred screening method for pulmonary hypertension (PH). The probability of PH is primarily assessed by estimating the right ventricular systolic pressure while the value of qualitative parameters is uncertain. The aim of our study was to evaluate the diagnostic yield of qualitative and quantitative parameters from routine echocardiography reports for PH diagnosis. ⋯ Qualitative parameters are frequently described in routine echocardiography reports and are valuable for the prediction of PH with a similar diagnostic accuracy as the estimation of right ventricular systolic pressure.
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Fever and pain in children, especially associated with infections, such as otitis media, are very common. In paediatric populations, ibuprofen and paracetamol (acetaminophen) are both commonly used over-the-counter medicines for the management of fever or mild-to-moderate pain associated with sore throat, otitis media, toothache, earache and headache. Widespread use of ibuprofen and paracetamol has shown that they are both effective and generally well tolerated in the reduction in paediatric fever and pain. ⋯ However, in the overdose situation, the toxicity of paracetamol is not only reached much earlier, but is also more severe and more difficult to manage as compared with an overdose of ibuprofen. There is clearly a need for advanced studies to investigate the safety of these medications in paediatric populations of different ages and especially during prolonged use. Finally, the recently reported association between frequency and severity of asthma and paracetamol use needs urgent additional investigations.