BMC research notes
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Meta Analysis
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
Tranexamic acid (TXA) is an antifibrinolytic drug used as a blood-sparing technique in many surgical specialties. The principal objective of our meta-analysis was to review randomized, controlled trials (RCT) comparing total blood loss and the number of patients receiving allogeneic blood transfusions with and without the use of TXA for knee (TKA) and hip (THA) arthroplasty. ⋯ TXA should be considered for routine use in primary knee and hip arthroplasty to decrease blood loss.