Surgery
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Postoperative ileus is a transient cessation of bowel motility that occurs after bowel resection (BR). Alvimopan, a peripherally acting mu-opioid receptor antagonist accelerated gastrointestinal (GI) recovery in 5 randomized, double-blind, phase III postoperative ileus trials. ⋯ These post hoc analyses support that alvimopan (12 mg) accelerates GI recovery across various patient populations.