Archives of general psychiatry
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Arch. Gen. Psychiatry · Dec 2011
Randomized Controlled Trial Multicenter StudyAdjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial.
No randomized trials have examined treatments for prescription opioid dependence, despite its increasing prevalence. ⋯ Prescription opioid-dependent patients are most likely to reduce opioid use during buprenorphine-naloxone treatment; if tapered off buprenorphine-naloxone, even after 12 weeks of treatment, the likelihood of an unsuccessful outcome is high, even in patients receiving counseling in addition to SMM.