Seminars in oncology
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The mainstay of screening for breast cancer is the mammogram. There are several randomized control trials that demonstrate a significant decrease in breast cancer mortality when compared to women without screening mammography included in their care. ⋯ With the introduction of digital mammography, other novel techniques such as stereo digital mammography (SDM) and tomosynthesis can reduce recall significantly without a negative effect on cancer detection. Magnetic resonance imaging (MRI) and ultrasound added to mammography can improve cancer detection for high-risk women but can have false positive consequences.
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Seminars in oncology · Feb 2011
Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening.
Optical imaging is an inexpensive, fast, and sensitive imaging approach for the noninvasive detection of human cancers in locations that are accessible by an optical imaging device. Light is used to probe cellular and molecular function in the context of cancer in the living body. ⋯ The optical signals can be endogenous contrasts that capture the heterogeneity and biological status of different tissues, including tumors, or extrinsic optical contrasts that selectively accumulate in tumors to be imaged after local or systemic delivery. The use of optical imaging is now being applied in the clinic and operating room for the localization and resection of malignant tumors in addition to screening for cancer.