The American journal of gastroenterology
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Am. J. Gastroenterol. · Apr 1995
Randomized Controlled Trial Comparative Study Clinical TrialGastrointestinal blood loss with low dose (325 mg) plain and enteric-coated aspirin administration.
The purpose of this study was to assess gastrointestinal blood loss with low dose (325 mg) plain and enteric-coated aspirin. ⋯ During acute and chronic ingestion, plain aspirin at a dose of 325 mg/day significantly increased gastrointestinal blood loss when compared to control or enteric-coated aspirin values, although enteric-coated aspirin values were also significantly increased compared to control. Gastric adaptation does not decrease blood loss with low dose aspirin consumption.