The American journal of gastroenterology
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Am. J. Gastroenterol. · Apr 2007
Meta AnalysisDiagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy.
Fecal calprotectin (FC) is a relatively new marker of intraluminal intestinal inflammation. Using meta-analytical techniques, the study aimed to evaluate the diagnostic precision of FC for inflammatory bowel disease (IBD) and colorectal cancer (CRC) in adults and children. ⋯ FC cannot be recommended as a screening test for CRC in the general population. FC appeared to offer a good diagnostic precision in distinguishing IBD from non-IBD diagnoses, with higher precision at a cutoff of 100 microg/g.