The American journal of gastroenterology
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Am. J. Gastroenterol. · Sep 2014
Randomized Controlled TrialGranulocyte colony-stimulating factor in severe alcoholic hepatitis: a randomized pilot study.
Severe alcoholic hepatitis has high short-term mortality. The aim of this study was to test the hypothesis that treatment of patients with alcoholic hepatitis with granulocyte colony-stimulating factor (G-CSF) might mobilize bone marrow-derived stem cells and promote hepatic regeneration and thus improve survival. ⋯ G-CSF is safe and effective in the mobilization of hematopoietic stem cells and improves liver function as well as survival in patients with severe alcoholic hepatitis.