Mymensingh medical journal : MMJ
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Randomized Controlled Trial Comparative Study
Comparative study of stress response to central venous cannulation under local anesthesia and general anesthesia in patients undergoing open heart surgery.
The open heart surgery like coronary artery bypass graft (CABG), repair of ventricular septal defect (VSD) and atrial septal defect (ASD), valve replacement need a circulatory arrest, which is normally safe under conventional hypothermia. During this time not only the heart and lungs are bypassed but also a wide range of haemodynamic manipulation is necessary. For this reason continuous arterial and central venous pressure monitoring are mandatory. ⋯ All data were analyzed by using Student's 't' test in Statistical Program for Scientific Study (SPSS). From the study, we can conclude that central venous cannulation under local anesthesia in patients for open heart surgery has no significant changes of haemodynamic and humoral stress response in comparison to those of under general anesthesia. So, central venous access device can be placed under local anesthesia supported by premedication and it produces no significant changes in preoperative stress response in patients for open heart surgery.