The British journal of ophthalmology
-
The role of orbital computed tomography (CT) in the management of retinoblastoma is reviewed. All 21 patients with retinoblastoma studied with high-resolution computed tomography had intraocular calcification demonstrable in at least one eye. 83% of tumours showed evidence of calcification on CT scan. ⋯ In patients under 3 years old in whom a retinoblastoma is suspected the presence of calcification on CT is virtually diagnostic of it. Patients with leucocoria without calcification on CT probably have a simulating lesion.
-
Contrast sensitivity was measured in the eyes of 200 consecutive patients attending the glaucoma family screening unit. One-third of the patients screened had an abnormal contrast sensitivity. Positive correlation (p less than 0.01) existed between this abnormal contrast sensitivity and cup : disc ratio, visual field loss, and age. No such correlation existed between contrast sensitivity and intraocular pressure.
-
In a 2-year prospective study of 76 patients with traumatic hyphaema seen at the Ahmadu Bello University Hospital, Kaduna, 75% were under 20 years of age. A low male to female ratio of 3 to 1 relative to other reports was noted. Hyphaema occurred in the left eye 1.6 times more often than in the right eye. ⋯ The final vision was worse as the level of hyphaema increased. Thus of 13 patients with vision of no perception of light, 8 (61.5%) had total hyphaema. The reasons for some of the differences from other reports are discussed and suggestions are offered as to ways of improving the visual outcome from the disease.
-
The lactic dehydrogenase (LDH) activity of the aqueous humour has been estimated in both eyes of 7 patients having uniocular retinoblastoma. In 1 patient the aqueous humour LDH activity in the healthy eye was above normal, but there was no clinical evidence of malignancy. ⋯ A high LDH activity persisted even after irradiation, though no tumour tissue was visible ophthalmoscopically. It is suggested that the estimation of the LDH activity in the aqueous humour of the healthy eye in cases of uniocular retinoblastoma might be of value in the early detection of a bilateral retinoblastoma.