Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Nov 2011
[Effects of hydrogen sulfide on pulmonary surfactant in rats with acute lung injury induced by lipopolysccharide].
To observe the changes of pulmonary surfactant (PS) in rats with acute lung injury(ALI) induced by lipopolysaccharide (LPS) and to explore the effects of hydrogen sulfide (H2S) on PS. ⋯ The decrease of PS is the important physiopathologic process of ALI induced by LPS. Exogenously applied H2S could attenuate the process of ALI that possibly because H2S could adjust the compose and secretion of PS.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Nov 2011
Randomized Controlled Trial[Clinical observation of injection of dexmedetomidine in anaesthesia for esophageal cancer operation].
To investigate the effects of administration of dexmedetomidine in anaesthesia for esophageal cancer operation. ⋯ Dexmedetomidine could effectively reduce the cardiovascular response to incubation and extubation in esophageal cancer operation patients. Propofol comsumption, fentanlyl comsumption and side effects were reduceed as well.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Aug 2011
[Changes of GABA-activated currents in isolated dorsal root ganglion neurons in rats with neuropathic pain].
To investigate the changes of GABA-activated currents in isolated dorsal root ganglion neurons in rats with neuropathic pain. ⋯ The data indicates that the chronic constriction injury change both the function of GABAA receptors of injury side and opposite side. The decrease of pre-synaptic inhibition of GABA may be the possible reason of neuropathic pain.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Aug 2011
[Penehyclidine hydrochloride inhibits glutamate release and related research in global brain ischemia/reperfusion rats].
To investigate the effect of penehyclidine hydrochloride on glutamate (Glu)release and N-methyl-D-aspartate receptor (NMDAR)1 expression in hippocampus CA1 with global cerebral ischemia/reperfusion rats. ⋯ Penehyclidine hydrochloride might has protective effect in hippocampus CA1 on global cerebral ischemia/reperfusion animals. The protective mechanism might be involved in inhibiting Glu release and NMDAR1 expression.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · May 2011
[Effects of ambroxol combined with low-dose heparin on TNF-alpha and IL-1beta in rabbits with acute lung injury].
To investigate the intervention and mechanism of ambroxol combined with low-dose heparin on oxidative stress, TNF-alpha and IL-1beta in rabbits with acute lung injury (ALI). ⋯ In ALI induced by OA, IL-1beta and TNF-alpha increases significantly and involved in the occurrence and development of ALI. Ambroxol combined with low-dose heparin can reduce lung cells oxidative stress to inhibit the release of IL-1beta and TNF-alpha, which play a role in the treatment of ALI.