Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Feb 2018
[Effects of 16 week aerobic exercise on baPWV and ABI of middle-aged and elderly patients].
To investigate the interventional effects of 16-week aerobic exercises on the elderly's arteriosclerosis and its mechanism. ⋯ Sixteen-week aerobic exercises could reduce baPWV and ABI levels, regulate blood pressure, blood lipids and lipid peroxides levels of the elderly evidently, thus improve the controlling quality of atherosclerosis.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Jun 2017
[The effects of NOX4 and TGF-βinvolved in airway remodeling of Chronic Obstructive Pulmonary Disease].
To investigate the role of nicotinamide adenine dinucleotide phosphate 4 (NADPH4,NOX4) and transforming growth factor-beta (TGF-β) involve in pathogenesis of airway remodeling in chronic obstructive pulmonary disease (COPD). ⋯ ①The airway remodeling of COPD is characterized by increasing hyperplasia of small airway smooth muscle.②Remodeling of airway smooth muscle associats with severity of airflow limitation in COPD patients. ③The expressions of NOX4, TGF-β and α-SMA in COPD epithelial cells and small airway smooth muscle cells are significantly enhanced. The expressions of NOX4, α-SMA and TGF-β are positively correlated with the severity of chronic obstructive pulmonary air flow, suggesting that TGF-β and NOX4 signaling may be involved in the development of chronic obstructive pulmonary disease airway remodeling.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Jun 2017
[Ameliorative effects and the mechanism of lyceum barbarum polysaccharide on insulin resistance of HepG2 cell].
To observe the effects of lyceum barbarum polysaccharide (LBP) on insulin resistance of HepG2 cells and investigate its possible mechanism. ⋯ Medium and high concentration of LBP can improve insulin resistance of HepG2 cell, its mechanisns may be associated with decreasing the level of oxidative stress and increasing the protein expressions of insulin signaling pathway.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · May 2017
[Effects of Dexmedetomidine on the levels of proinflammatory mediators IL-1βand TNF-α in pulmonary ischemia/reperfusion injury rats and the mechanisms].
To evaluate the effects and mechanism of the Dexmedetomidine on the levels of proinflammatory mediators interleukin 1 beta (IL-1β) and tumor necrosis factor-α(TNF-α) in ischemia/reperfusion(I/R)rats. ⋯ Dexmedetomidine can alleviate ischemia/reperfusion injury in rat lung through lowering the level of proinflammatory mediators IL-1β and TNF-α,the possible mechanism may be through stimulation of α2 adrenaline receptors.
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Zhongguo Ying Yong Sheng Li Xue Za Zhi · Feb 2017
[Protective effects of xuebijing on the acute lung injury in rats].
To investigate the protective effects of xuebijing (Traditional Chinese Medicine)on the acute lung injury in rats. ⋯ Xuebijing could alleviate lipopolysaccharide-induced ALI,and its pharmacological mechanism may be related to down-regulation the protein expressions of TNF-α and HMGB1 and the serum level of MDA and up-regulation the protein expression of IL-10 and the serum level of SOD and the high-dose is more effective.