Dermatologica
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Hereditary disorders of keratinization may be a considerable handicap. Oral treatment with retinoids has been shown to be effective in many of these diseases. In the group of ichthyoses, the best results can be obtained in the various types of nonbullous congenital ichthyosis (erythrodermic autosomal recessive lamellar ichthyosis, nonerythrodermic autosomal recessive lamellar ichthyosis, autosomal dominant lamellar ichthyosis). ⋯ Papillomatous epidermal nevi should also be excluded because they do not respond to the drug. Hailey-Hailey disease may even be worsened by this treatment. According to our experience, oral retinoid therapy has no effect in monilethrix.
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Review
Basal cell carcinoma of the skin recurrence rate after different types of treatment. A review.
On the basis of own investigations and a survey of the literature, it is shown that the recurrence rate following various types of treatment used for basal cell carcinoma (BCC) is somewhat higher than generally assumed. Irrespective of the method used, the results obtained after treatment of recurrent BCCs are less favorable. Consequently, it is strongly recommended that patients be closely controlled for a period of years following treatment and that only specially trained doctors carry out the treatment. The possibility of centralizing treatment of BCC of the skin to dermatological units is put forward.