Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Sep 1997
Randomized Controlled Trial Comparative Study Clinical TrialIntermittent bolus versus patient-controlled epidural morphine for postoperative analgesia.
Patient-controlled epidural analgesia (PCEA) is a technique that combines the flexibility and convenience of PCA with the intrinsic analgesic efficacy of epidurally administered opioids. The aim of this study is to compare the analgesic and side effects of intermittent bolus injections of epidural morphine with PCEA using morphine during the first 24 h after elective low abdominal surgery. ⋯ PCEA with morphine decreases morphine consumption and with less adverse effects than intermittent bolus of epidural morphine. PCEA with morphine is an acceptable alternative to epidural morphine after low abdominal surgery.
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Acta Anaesthesiol. Sin. · Sep 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of neuromuscular action of rocuronium, a new steroidal non-depolarizing agent, with vecuronium.
Rocuronium is a new nondepolarizing muscle relaxant. It features a rapid onset and lack of histamine release: It has an intermediate onset of action as vecuronium. The purpose of this study was to compare the neuromuscular action and condition of intubation after a bolus dose of rocuronium or vecuronium (2 x ED90). We also compared the duration of relaxation after intubation and maintenance doses of each drug. ⋯ We conclude that rocuronium provides a more rapid onset of action than that of vecuronium. Rocuronium is an intermediate-acting muscle relaxant as vecuronium with good to excellent intubation condition. It may be an useful alternative to vecuronium for rapid tracheal intubation.