Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Mar 1997
Randomized Controlled Trial Clinical TrialPriming technique accelerates the onset time of mivacurium in children during halothane anesthesia.
Mivacurium is considered a relaxant suitable for tracheal intubation in children due to its rapid onset. We compared the neuromuscular effects of mivacurium, with and without priming, in children undergoing elective surgery during halothane anesthesia. ⋯ Priming technique can significantly accelerates the onset of mivacurium in the pediatric patients under halothane anesthesia.
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Acta Anaesthesiol. Sin. · Dec 1996
Randomized Controlled Trial Comparative Study Clinical TrialProphylaxis against acid aspiration in regional anesthesia for elective cesarean section: a comparison between oral single-dose ranitidine, famotidine and omeprazole assessed with fiberoptic gastric aspiration.
Acid aspiration syndrome is still an important cause which contributes to maternal mortality in obstetric anesthesia. In this study, we compared famotidine, ranitidine, omeprazole with placebo for prophylaxis against aspiration pneumonitis in elective Cesarean section under regional anesthesia. ⋯ Our data demonstrated that parturients under regional anesthesia were at a higher risk of aspiration pneumonitis than generally thought. Single dose of ranitidine or famotidine administered orally three hours before surgery provided a more effective means to control and neutralize gastric secretion than omeprazole in parturients.
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Acta Anaesthesiol. Sin. · Dec 1996
Randomized Controlled Trial Clinical TrialCo-administration of midazolam decreases propofol dose during anesthesia in endoscopic laryngeal microsurgery.
Propofol is commonly used in total intravenous anesthesia (TIVA) for brief surgical procedures because it offers rapid recovery and has fewer side effects. However, concomittent use of other adjuvant agents has been considered so that the same anesthetic effects can be achieved at lower doses of propofol which is more expensive without compromising rapid recovery and increasing the adverse effects. This study was therefore designed to evaluate the co-administration of midazolam and propofol during anesthesia for endoscopic microsurgery and test its influences on the consumption of propofol and the quality of anesthesia. ⋯ Our result suggests that co-administration of midazolam and propofol in TIVA appears to be safe, effective, and economic alternative to that with propofol alone. The effects were synergic but side effects were not.
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Acta Anaesthesiol. Sin. · Sep 1996
Randomized Controlled Trial Clinical TrialConscious sedation by low dose propofol infusion during spinal anesthesia for cesarean section.
A simple sedative technique without inducing oversedation or amnesia for birth experience would be necessary for patients undergoing Cesarean section receiving regional anesthesia. Clinical effects and dose requirement of intravenous propofol infusion were evaluated for this purpose. ⋯ Intravenous infusion of propofol with a rate of 3-4 mg/kg/h after 0.3-0.4 mg/kg bolus injection is a sale, simple and satisfactory intraoperative postdelivery sedation technique in elective patients undergoing Cesarean section under spinal anesthesia.
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Acta Anaesthesiol. Sin. · Jun 1996
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of lidocaine, fentanyl, and esmolol for attenuation of cardiovascular response to laryngoscopy and tracheal intubation.
Laryngoscopy and tracheal intubation are known to increase sympathetic activity that may be detrimental to patients with pre-existing ischemic or hypertensive heart diseases. In order to alter the hyperdynamic consequences resulting from intubation during induction of general anesthesia, we chose esmolol, an ultra-short acting cardioselective beta-adrenergic blocker, to attenuate the cardiovascular responses during tracheal intubation in patients undergoing elective surgery. The efficacy of esmolol in this regard was carefully evaluated. ⋯ Results of this study showed that only esmolol could reliably offer protection against the increase in both HR and SBP, low dose of fentanyl (3 micrograms/kg) prevented hypertension but not tachycardia, and 2 mg/kg lidocaine had no effect to blunt adverse hemodynamic responses during laryngoscopy and tracheal intubation.