Clinical orthopaedics and related research
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Clin. Orthop. Relat. Res. · Jul 2017
Vancomycin Prophylaxis for Total Joint Arthroplasty: Incorrectly Dosed and Has a Higher Rate of Periprosthetic Infection Than Cefazolin.
In total joint arthroplasty (TJA), vancomycin is used as perioperative antibiotic prophylaxis in patients with penicillin allergy or in patients colonized with methicillin-resistant Staphylococcus aureus (MRSA). Although vancomycin dosing should be weight-based (15 mg/kg), not all surgeons are aware of this; a fixed 1-g dose is instead frequently administered. ⋯ Level III, therapeutic study.
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Clin. Orthop. Relat. Res. · Jul 2017
Have the Causes of Revision for Total and Unicompartmental Knee Arthroplasties Changed During the Past Two Decades?
Revisions after knee arthroplasty are expected to increase, and the epidemiology of failure mechanisms is changing as new implants, technology, and surgical techniques evolve. ⋯ Level III, therapeutic study.