Anaesthesia, critical care & pain medicine
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Anaesth Crit Care Pain Med · Jun 2021
Randomized Controlled TrialAlveolar recruitment manoeuvre results in improved pulmonary function in obese patients undergoing bariatric surgery: a randomised trial.
Perioperative ventilation is an important challenge of anaesthesia, especially in obese patients: body mass index is correlated with reduction of the pulmonary volume and they develop significantly more perioperative atelectasis and pulmonary complications. The alveolar recruitment manoeuvre is the most effective technique to reverse atelectasis. However, the clinical benefit on lung function in the perioperative period is not clear. ⋯ No significant differences were found for secondary outcomes. No patient was excluded from the recruitment manoeuvre group for intolerance to the manoeuvre. Recruitment manoeuvre is safe and effective in reducing early pulmonary dysfunction in obese patients undergoing bariatric surgery.
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Anaesth Crit Care Pain Med · Dec 2020
Randomized Controlled TrialAtelectasis prevention during anaesthesia using high-flow nasal cannula therapy: A paediatric randomised trial using MRI images.
Atelectasis frequently occurs early on during anaesthesia in children. We hypothesised that positive expiratory pressure (PEP) generated via high-flow nasal cannula (HFNC) could prevent atelectasis in non-intubated children under general anaesthesia. The objective was to compare the volume of atelectasis present in patients treated via HFNC to that of patients treated via a face bag-mask without PEP. The outcome used for this comparison was the ratio of the atelectasis volume to the total pulmonary volume. ⋯ HFNC was associated with a lower atelectasis lung ratio compared to using a face bag-mask during anaesthesia for children maintained with spontaneous ventilation. Registered on Clinicaltrials.gov: NCT03592589.
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Anaesth Crit Care Pain Med · Dec 2019
Randomized Controlled Trial Comparative StudyNorepinephrine versus phenylephrine infusion for prophylaxis against post-spinal anaesthesia hypotension during elective caesarean delivery: A randomised controlled trial.
Norepinephrine infusion is practical to use to reduce hypotension during caesarean section under spinal anaesthesia, and is non-inferior compared with phenylephrine.
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Anaesth Crit Care Pain Med · Dec 2019
Letter Randomized Controlled Trial Comparative StudyImmediate haemodynamic impact response to a mini-fluid challenge is independent of fluid type: A post-hoc analysis of a randomised double blinded controlled trial.