West African journal of medicine
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Randomized Controlled Trial Comparative Study
Comparison of unreamed interlocking nail and external fixation in open tibia shaft fracture management.
The management of open tibia fractures remains controversial despite increase in its incidence. Some surgeons avoid internal fixations for fear of infection while others have demonstrated its superiority. Identifying an optimal management modality is of utmost benefit to our patients. Study objectives were to compare the rate of infection and mean duration to healing in the management of open tibia fractures using unreamed interlocking intramedullary nail and external fixation. ⋯ The risk of wound infection was observed to be higher in this study with the use of external fixation in the management of open tibia fractures compared with unreamed interlocking intramedullary nail.
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Randomized Controlled Trial Comparative Study
Caesarean section outcome in eclamptic patients: a comparison of infiltration and general anaesthesia.
Eclamptic patients undergoing caesarean delivery present extreme management problems for both obstetricians and anaesthetists. These problems reflect a poor maternal and perinatal outcome. ⋯ Local infiltrative anaesthesia appears to have a better maternal and perinatal outcome than general anaesthesia for eclamptic patients undergoing caesarean section.
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Randomized Controlled Trial Comparative Study Clinical Trial
Efficacy and safety of misoprostol in induction of labour in a Nigerian tertiary hospital.
Misoprostol - a stable prostaglandin E1 analogue- is effective and safe in the induction of labour. There is paucity of information about the use of misoprostol for labour induction in Nigeria. ⋯ The efficacy of misoprostol in the induction of third trimester labour is comparable to oxytocin. The risk of ruptured uterus associated with misoprostol appears higher than that of oxytocin in the induction of labour. Further studies are needed to verify this observation in our setting.
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Randomized Controlled Trial Comparative Study
Clinical comparison of cardiorespiratory effects during unilateral and conventional spinal anaesthesia.
Spinal anaesthesia is widely employed in clinical practice but has the main drawback of post-spinal block hypotension. Efforts must therefore continue to be made to obviate this setback ⋯ Compared to conventional spinal anaesthesia, unilateral spinal anaesthesia was associated with fewer cardiovascular perturbations. Also, the type of spinal block instituted affected neither the respiratory rate nor the arterial oxygen saturation.
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Randomized Controlled Trial
Efficacy of nebulized furosemide in children with moderate attack of asthma.
Bronchodilators are the most commonly used drugs for asthma. However, alternative treatment is necessary for those patients who experience adverse effects from bronchodilators. ⋯ Combination of both furosemide and albuterol led to significant increase in peak flow rate but it did not significantly affect FEV1, FVC, FEF 25-75, respiratory rate, SaO2 or clinical scores as compared to other groups. There were no significant adverse effects from the three drugs used.