The American journal of pediatric hematology/oncology
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Am J Pediatr Hematol Oncol · Aug 1994
Current controversy: is computed tomography scan of the chest needed in patients with Wilms' tumor?
Reports from the National Wilms' Tumor Study (NWTS) Group on the subject of chest computed tomography (CT) versus chest radiograph for the detection of lung metastases from Wilms tumor are reviewed. ⋯ All children should have the benefit of the most sensitive imaging available, including CT, to detect tumor spread.
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Am J Pediatr Hematol Oncol · Aug 1994
Comparative StudyPrevention of chemotherapy-induced emesis with granisetron in children with malignant diseases.
In a prospective crossover study, we evaluated the safety and antiemetic activity of granisetron, a 5-hydroxytryptamine3 (5-HT3) receptor antagonist, compared with conventional antiemetics regimen, including metoclopramide, in pediatric cancer patients. ⋯ Granisetron 40 micrograms/kg is well tolerated and more effective than are conventional antiemetic regimens containing metoclopramide for children receiving cancer chemotherapy.