Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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To investigate changes in axonal persistent Na(+) currents in patients with neuropathic pain and the effects of mexiletine, an analogue of lidocaine, on axonal excitability properties. ⋯ Latent addition can be used for indirect in vivo monitoring of nodal Na(+) currents in large sensory fibers, and future studies using this approach in small fibers would provide new insights into the peripheral mechanism of neuropathic pain.
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Comparative Study
Effect of pain on the modulation in discharge rate of sternocleidomastoid motor units with force direction.
To compare the behavior of sternocleidomastoid motor units of patients with chronic neck pain and healthy controls. ⋯ These observations suggest that chronic neck pain affects the change in neural drive to muscles with force direction.