Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Randomized Controlled Trial Comparative Study
Comparison of high gamma electrocorticography and fMRI with electrocortical stimulation for localization of somatosensory and language cortex.
We investigated the contribution of electrocortical stimulation (ECS), induced high gamma electrocorticography (hgECoG) and functional magnetic resonance imaging (fMRI) for the localization of somatosensory and language cortex. ⋯ HgECoG and fMRI make the cortical mapping procedure more flexible not only by identifying priority cortical sites for ECS or when ECS is not feasible, but also when ECS does not provide any result.
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Randomized Controlled Trial
Startling acoustic stimuli can evoke fast hand extension movements in stroke survivors.
A startling loud acoustic stimulus can involuntarily elicit planned movements, a phenomenon referred to as startReact. Following stroke, startReact elbow flexion in stroke survivors are improved from voluntary movements. Specifically, startReact elbow flexion in unimpaired individuals is not statistically different from stroke survivors in terms of onset latency and muscle activation patterns. As hand movements are particularly impacted by stroke, our objective was to determine if startReact was intact in the hand following stroke. ⋯ An intact startReact response indicates that this reflex may be an attractive therapeutic target for initiating hand extension in stroke survivors.
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Randomized Controlled Trial
Abnormal cortical activation in females with acute migraine: a magnetoencephalography study.
The objective of this study was to investigate functional abnormalities of the brain in females with migraine using magnetoencephalography (MEG) and a finger-tapping task. ⋯ These findings may help to identify neurophysiological biomarkers for studying mechanisms of migraine, and may facilitate to develop new therapeutic strategies for migraine by alterations in cortical excitability.
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Randomized Controlled Trial
Effects of mindfulness-based cognitive therapy on neurophysiological correlates of performance monitoring in adult attention-deficit/hyperactivity disorder.
To examine whether mindfulness-based cognitive therapy (MBCT) would enhance attenuated amplitudes of event-related potentials (ERPs) indexing performance monitoring biomarkers of attention-deficit/hyperactivity disorder (ADHD). ⋯ MBCT suggests having comparable modulation on performance monitoring ERP amplitudes as pharmacological treatments. Further study and development of MBCT as a treatment for ADHD is warranted, in addition to its potential scope for clinical applicability to broader defined externalising disorders and clinical problems associated with impairments of the prefrontal cortex.
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Randomized Controlled Trial
Sensory correlates of pain in peripheral neuropathies.
To characterize sensory threshold alterations in peripheral neuropathies and the relationship between these alterations and the presence of pain. ⋯ There is a complex relationship between the loss or functional deficit of large and especially small sensory nerve fibers and the development of pain in peripheral neuropathy.