Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Spinal neuronal function is impaired after a severe spinal cord injury (SCI) and can be assessed by the analysis of spinal reflex (SR) behavior. We applied transcutaneous spinal direct current stimulation (tsDCS) and locomotor activity, to determine whether the excitability of spinal neuronal circuitries underlying locomotion can be modulated after motor complete SCI. ⋯ This novel, noninvasive approach might be used as a tool to excite spinal neuronal circuitries. If applied repetitively within a training approach, anodal tsDCS might prevent adverse alterations in spinal reflex function in severely affected SCI subjects, i.e., a manifestation of a spinal neuronal dysfunction taking part below the level of a spinal lesion.
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To evaluate the utility of near-infrared spectroscopy (NIRS) and transcranial Doppler (TCD) parameters as potential markers for amnestic mild cognitive impairment (aMCI). ⋯ The reduction of TOI may be considered a new marker for aMCI, especially when combined with the increase of PI in MCA.
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Multicenter Study
Intraoperative monitoring of carotid endarterectomy by transcranial motor evoked potential: a multicenter study of 600 patients.
This study was to investigate the utility of motor evoked potential monitoring elicited by transcranial electrical stimulation (tcMEP) during CEA in addition to the established median nerve somatosensory evoked potentials (mSSEPs). ⋯ TcMEPs seem to improve postoperative outcome, especially in case of a timely correction of cerebral ischemia.
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To determine the percentage change in somatosensory evoked potential amplitude and the duration of spinal cord compression that can be tolerated intraoperatively in a rat model before there are significant post-operative functional deficits. ⋯ This study is an important first step in providing basic science evidence for the establishment of acceptable "alarm criteria" during spinal surgery.