Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Measurement of thermal pain thresholds is an essential part of quantitative sensory testing (QST). However, databases of QST show limitations due to large inter-individual variations including unreasonably low thresholds for thermal pain, lack of data on intra-individual variations over time and on the subjects' perception at threshold. This study sought to reduce inter-individual variations, investigated the reproducibility of measurements of thermal pain thresholds and included evaluation of thermally induced perceptions. ⋯ Further approaches are needed to reduce variability of thermal pain thresholds; however, good reproducibility of thermal pain thresholds and thermally induced perceptions warrants consideration of their use in larger longitudinal studies.
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Short-interval intracortical inhibition (SICI) is a widely used paired-pulse transcranial magnetic stimulation (TMS) measure to assess inhibition in human motor cortex. However, facilitatory processes may contaminate SICI under certain conditions. Here, we specifically address the contribution of short-interval intracortical facilitation (SICF). ⋯ SICF may contribute to apparently reduced SICI in patients with neurological or psychiatric disorders.
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To investigate the anticipatory neural processes associated with the interruptive effects of pain anticipation on attention. ⋯ Individuals with greater anticipatory midcingulate responses may be predisposed to developing chronic pain and hypervigilance toward clinical pain symptoms.
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Case Reports
Electroencephalography burst suppression in a patient with dengue encephalopathy: A case report.
To report a rare case of dengue fever presenting with reversible encephalopathy and burst suppression in the EEG. ⋯ EEG burst suppression does not necessarily suggest a poor prognosis in patients with dengue fever.
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Clinical Trial
Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain.
To test the co-occurrence and interrelation of ictal activity and cortical spreading depressions (CSDs) - including the related periinfarct depolarisations in acute brain injury caused by trauma, and spontaneous subarachnoid and/or intracerebral haemorrhage. ⋯ ECoG recordings in brain injury patients provide insight into pathophysiological mechanisms, which are not accessible by scalp EEG recordings.