International journal of burns and trauma
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Stem cell therapy application is at the vanguard of regenerative medicine across all medical disciplines. Stem cells are of special interest in burn wounds, as they have multiple potential indications for application; including - accelerating wound healing, improving skin regeneration to incorporate skin appendages, reducing fibrosis and improving scarring. ⋯ Stem cells accelerate burn wound healing by inducing neo-angiogenesis, collagen deposition and granulation tissue formation. They modulate the inflammatory response and reduce the risk of infection. They can regenerate skin appendages and halt he zone of stasis in acute burn injury. However with these pre-clinical animal model studies we must be cautious with our interpretation of this novel therapy.