Prague medical report
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Prague medical report · Jan 2008
Quantitative analysis of procalcitonin after pulmonary endarterectomy in relation to cytokines and C-reactive protein.
Endarterectomy of the pulmonary artery (PEA) is a potential curative treatment method for selected patients with chronic thromboembolic pulmonary hypertension (CTEPH). The postoperative course after PEA is associated with high rate of early postoperative mortality, which ranges from 5 to 23%. The aim of this prospective clinical study was to assess the time course of procalcitonin (PCT) after uncomplicated PEA in relation to other inflammatory parameters. ⋯ Postoperative PCT culmination was delayed in alignment to pro-inflammatory mediators as IL-6 and IL-8. Positive correlation between PCT and IL-6 corresponded with the role of IL-6 in PCT induction in perioperative phase. Plasma PCT estimation extended to a measurement of CRP and IL-6 may become a useful complementary examination in early postoperative period after PEA.
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Prague medical report · Jan 2008
Biography Historical ArticleThe life-work of Prof. MUDr. Zdenek Lojda, Dr.Sc., Dr. Med. et Iur. h.c.
Professor Zdenek Lojda, MD., Dr. Sc., Dr. Med.h.c., Dr. ⋯ In 1962 professor Frankenberger retired and Lojda left the Institute of Embryology for the 4th internal clinic to work in the Laboratory of Angiology housed at the 1st (Hlava) Institute of Pathologic Anatomy. This step influenced Lojda's professional occupations: in the Laboratory of Angiology he studied enzymes of blood vessel wall; the problems in gastroenterology solved at the 4th internal clinic and teaching hospital brought him to issues connected with enzyme garniture of the intestinal mucosal epithelium; his engagement at the Hlava Institute where he worked as well as house officer and later as pathology teacher caused that he subordinated his interest in enzyme garniture of various tissues to study and explanation of pathological processes using functional morphology. In years 1966 to 1975 he earned his master degree in pathology, he habilitated in pathology and was promoted to a professorship in pathology.