Journal of laparoendoscopic surgery
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J Laparoendosc Surg · Apr 1996
Randomized Controlled Trial Comparative Study Clinical TrialComparative stress hormone changes during helium versus carbon dioxide laparoscopic cholecystectomy.
Laparoscopic surgery has been termed minimally invasive surgery by advocates of this technology. It has been demonstrated previously that using carbon dioxide for insufflation produces a respiratory acidosis due to transperitoneal absorption of gas. Insufflation with helium does not create this acidosis. ⋯ Laparoscopic cholecystectomy produces significant increases in stress hormone levels. Prevention of acidosis with helium insufflation does not appear to protect against increases in stress hormones. Epinephrine levels with helium insufflation are higher than with CO2, and elevations in stress hormones suggest that laparoscopic cholecystectomy is not physiologically minimally invasive.