BJU international
-
Randomized Controlled Trial Multicenter Study
Duloxetine compared with placebo for treating women with symptoms of overactive bladder.
To evaluate duloxetine (a serotonin-noradrenaline reuptake inhibitor) in women with symptoms of overactive bladder (OAB), as it has been shown to increase the bladder capacity in an animal model. ⋯ In this trial, duloxetine was better than placebo for treating women with 'wet' and 'dry' symptoms of OAB associated with DOA or a bladder capacity of <400 mL.